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Biocompatibility is a crucial factor in UHPLC systems when dealing with bioanalysis. While stainless steel components are commonly used in UHPLC systems due to their durability and cost-effectiveness, they pose significant challenges for certain bioanalytical applications. Issues like corrosion under high salt concentrations and unwanted interactions with samples such as proteins, highlight the need for materials that do not affect the application they are part of, referred to as a biocompatible system.

This white paper provides insight into biocompatibility based on various analytical experiments to show the importance of using the right material for your application.